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Optical techniques for advancement of photodynamic therapy: from model experiments to clinical studies

机译：光学技术促进光动力疗法的发展：从模型实验到临床研究

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摘要

Progress in photodynamic therapy (PDT) requires development of novel protocols. We report on performance of PDT employing chlorine-based photosensitizers and irradiation at wavelengths of 405 and 660 nm with monitoring by fluorescence imaging (FI) and optical coherence tomography (OCT). The study includes numerical simulations, model and animal experiments, as well as clinical monitoring.

机译：光动力疗法（PDT）的进展需要开发新的方案。我们报告了采用氯基光敏剂的PDT的性能以及在405和660 nm波长处的照射，并通过荧光成像（FI）和光学相干断层扫描（OCT）进行了监测。该研究包括数值模拟，模型和动物实验以及临床监测。

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《》|2018年|463-463|共1页
会议地点 St. Petersburg(RU)
作者
M.Yu. Kirillin; M.A. Shakhova; A.V. Khilov; D.A. Loginova; E.A. Sergeeva; A.E. Meller; D.A. Sapunov; V.V. Perekatova; I.V. Turchin; N.Yu. Orlinskaya; A.V. Shakhov;
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Institute of Applied Physics RAS Nizhny Novgorod Russia;

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关键词
Radiation effects; Monitoring; Medical treatment; Fluorescence; Optical imaging; Skin;

机译：辐射效应；监控；药物治疗;荧光;光学成像；皮肤;

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1. Techniques for delivery and monitoring of TOOKAD (WST09)-mediated photodynamic therapy of the prostate: Clinical experience and practicalities [J] . Weersink RA, Bogaards A, Gertner M, Journal of Photochemistry and Photobiology, B. Biology: Official Journal of the European Society for Photobiology . 2005,第3期

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2. Vascular damage after photodynamic therapy of solid tumors: a view and comparison of effect in pre-clinical and clinical models at the University of Louisville. [J] . Fingar VH, Taber SW, Haydon PS, In vivo. . 2000,第1期

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4. Optical techniques for advancement of photodynamic therapy: from model experiments to clinical studies [C] . M.Yu. Kirillin, M.A. Shakhova, A.V. Khilov, International Conference on Laser Optics . 2018

机译：光动力疗法推进的光学技术：从模型实验到临床研究
5. Non-invasive optical techniques to track dynamic processes during photodynamic therapy. [D] . Zawada, Robert H. 2004

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6. Overall Results for a National Program of Photodynamic Therapy for Basal Cell Carcinoma: A Multicenter Clinical Study to Bring New Techniques to Social Health Care [O] . Hilde Harb Buzzá, Lilian Tan Moriyama, José Dirceu Vollet-Filho, 2019

机译：一项针对基础细胞癌的光动力疗法国家计划的总体结果：一项多中心临床研究旨在为社会卫生保健带来新技术
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Optical techniques for advancement of photodynamic therapy: from model experiments to clinical studies

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