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Radiomics Based Analysis of Breast Tumors in DCE-MRI due to Neoadjuvant Treatment Therapy

机译:Neoadjuvant治疗疗法DCE-MRI乳腺肿瘤的基于辐射瘤分析

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Breast cancer is the utmost frequent cancer amid women. The efficiency of cancer treatments on tumor development is carried out using a most sensitive method dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Neoadjuvant chemotherapy (NAC) treatment is widely used in patients for early prediction of breast cancer. The development of extraction of high throughput of features is referred to radiomics. The purpose of this study is to determine the capability of radiomic features in the breast region respond to the treatment. Radiomic analysis was performed on 20 studies of 10 patients using DCE-MRI. A total of 94 three-dimensional radiomic features were extracted and examined statistically. Results explain that the five features 90 and 99 percentile of histogram intensity, mean 3D, variance 3D, and short-run emphasis are significant with p-value from 0.0025 to 0.0694. Hence, these radiomic features are potency to identify the ambivert changes in the breast region during the follow-ups.
机译:乳腺癌是女性中最常见的癌症。使用最敏感的方法动态对比度增强磁共振成像(DCE-MRI)进行癌症治疗对肿瘤发展的效率。 Neoadjuvant化疗(NAC)治疗广泛用于患者早期预测乳腺癌。提取高吞吐量的提取的开发被称为辐射族学。本研究的目的是确定乳腺区域的射出物特征的能力响应治疗。在20名患者使用DCE-MRI的研究中进行射线瘤分析。在统计上提取并检查了94个三维射出物特征。结果解释了五个特征90和99百分位的直方图强度,平均三维,方差3D和短期强调,P值显着,从0.0025到0.0694。因此,这些射出特征是效力,以在随访期间识别乳房区域的天气变化。

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