Development of Simple Digital Image Acquisition System for an Accurate Quantification of Corneal Arcus Formation

摘要

Corneal Arcus is a circular ring of lipid secretion that is deposited in the periphery of cornea. This ring is normally found in elderly people (a.k.a. arcus senilis) or even in younger ones suffering from metabolic syndrome (a.k.a. arcus juvenilis). Many researchers have confirmed that the ring have diagnostic values, i.e. as predictor for coronary artery diseases and lipid stratification. Efforts to develop flexible, low-cost, but also an accurate acquisition system will be described. The system is constructed from commercially available plastic welding goggle, equipped with a Logitec C525 webcam and LEDs lighting system powered through USB cable. Steps of calibration procedures were then implemented, in order to produce equally-magnified as well as calibrated preprocessed images for further accurate quantification steps. The developed acquisition system can produce eye images with excellent precision (%RSD = 2.38%) as well as highly accurate quantification (with error 0 - 4%).