Effects of Dietary Manganese on Oxidative Damage of the Neurons in Cocks

摘要

To investigate the Manganese(Mn)-induced toxicity on crucial oxidative damage parameters on brain of birds, 50-day-old male Hyline cocks were fed either a commercial diet or a Mn-supplemented diet. The following were determined: restraining ability to OH·, the activities of Na~+-K~+-ATPase, Mg~(2+)-ATPase and Ca~(2+)-ATPase, the activities of succinate dehydrogenase (SDH) and Calcineurin (CaN); Exposure to Mn significantly lowered restraining ability to OH·, the activities of ATP enzymes, activities of SDH and CaN. These findings suggested that Mn exposure resulted in the oxidative damage of cock cerebral tissue.