Mechanical Properties of Poly (ε-caprolactone)/ Polyethylene Terephthalate Composite Prototype Small Diameter Vascular Graft

摘要

The purpose of the vascular grafts or implantation is not only to keep a patient alive,but for the patient to continue with their normal lives.Polyethylene terephthalate (PET) has been successfully used in large diameter grafts; unfortunately,small diameter grafts were failures.Due to surface forces,blood plasma proteins are adsorbed by the graft,resulting vessel reclosure Poly (ε-caprolactone) (PCL) is a promising biodegradable polymer with a longer degradation time.The mechanical properties of the pure PCL membrane cannot meet the requirement.The aim of this study is to develop new vascular graft from PCL reinforced with PET monofilament weft-knitted tube fabric.The PET fabrics were knitted using small single jersey knitting machine.Then PCL solution was coated outside and inside of the weft-knitted fabric with a PTFE rod,and the pure PCL tube was taken as a control.The samples were dried by freeze drying method.The results have shown that the new vascular grafts have good porosity.In addition the tensile properties,elastic recovery and the suture retention strength of the new prototype vascular grafts were improved compared with pure PCL vascular graft,which could be used in clinical application.