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Spatiotemporal PET Reconstruction Using ML-EM with Learned Diffeomorphic Deformation

机译:使用ML-EM与学习的扩散形式变形的时空宠物重建

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Patient movement in emission tomography deteriorates reconstruction quality because of motion blur. Gating the data improves the situation somewhat: each gate contains a movement phase which is approximately stationary. A standard method is to use only the data from a few gates, with little movement between them. However, the corresponding loss of data entails an increase of noise. Motion correction algorithms have been implemented to take into account all the gated data, but they do not scale well in computation time, especially not in 3D. We propose a novel motion correction algorithm which addresses the scalability issue. Our approach is to combine an enhanced ML-EM algorithm with deep learning based movement registration. The training is unsupervised, and with artificial data. We expect this approach to scale very well to higher resolutions and to 3D, as the overall cost of our algorithm is only marginally greater than that of a standard ML-EM algorithm. We show that we can significantly decrease the noise corresponding to a limited number of gates.
机译:由于运动模糊,排放断层摄影中的患者运动会降低重建质量。在稍微的情况下,改善数据的改善:每个门包含近似静止的移动阶段。标准方法是仅使用来自少量盖茨的数据,它们之间的运动很小。但是,相应的数据丢失需要增加噪声。已经实现了运动校正算法以考虑所有门控数据,但它们在计算时间内不会展示很好,尤其是在3D中。我们提出了一种新颖的运动校正算法,它解决了可扩展性问题。我们的方法是将增强的ML-EM算法与基于深度学习的运动注册组合。培训是无人监督,人工数据。我们预计这种方法可以很好地扩展到更高的分辨率和3D,因为我们的算法的总成本仅略高于标准ML-EM算法。我们表明我们可以显着降低对应于有限数量的栅极的噪声。

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