The influence of the early operation intervention on the prognosis of neonatal necrotizing enterocolitis

摘要

Objective: To investigate the treatment effect of the early operation on the NEC disease. Methods: A retrospective analysis of our Hospital in recent 8 years, neonatal and pediatric surgery in the diagnosis and treatment of neonatal necrotizing enterocolitis cases. According to the modified Bell stage, Bell stage IIB 44 cases were divided into two groups: immediate operation group and non-immediate operation group. The cases of non-immediate operation group were treated conservatively, and would get surgical treatment when they get worse. The survival children were followed up to 6 months. Clinical data were retrospectively analyzed, including the survival rate and the incidence of incomplete intestinal obstruction. Results: About 50% of the Bell stage IIB cases developed into Bell stage III cases. The survival rate of the immediate operation group was obviously more than that of non-immediate operation group (87.5%vs57.1%) (P<0.05). And the incidence of incomplete intestinal obstruction of the immediate operation group was obviously less than that of non-immediate operation group (14.3%vs56.3%) (P<0.05). Conclusion: Early operation intervention can improve the survival rate of the NEC children obviously, and reduce the incidence of incomplete intestinal obstruction.