The related study of whitening efficacy of ginseng extract-ginsenoside Rb1

摘要

Objective: The effect of ginsenoside Rbl on in vitro mushroom tyrosinase and the proliferation of B16 melanocyte were studied. Method: The detection of in vitro activity of mushroom tyrosinase; The determination of cell proliferation rate. Result: The inhibition rate of Rbl samples at different concentrations to in vitro mushroom tyrosinase is obviously lower than arbutin with an inhibition rate between ± 0.05. The effect of ginsenoside Rbl on the proliferation of B16 melanocyte is changed along with the changes of concentration. Conclusion: There is no obviously effect of ginsenoside Rbl on in vitro activity of mushroom tyrosinase. When the concentration is lower than 125 pg/ml, the proliferation of B16 melanocyte is promoted. But the proliferation of B16 melanocyte is depressed with the concentration of ginsenoside Rbl above 125 μg/ml.