Contrasting of biotissue layers in OCT images after application of mechanical compression is discussed. The study is performed on ex vivo samples of human rectum, and in vivo on skin of human volunteers. We show that mechanical compression provides contrasting of biotissue layer boundaries due to different mechanical properties of layers. We show that alteration of pressure from 0 up to 0.45 N/mm2 causes contrast increase from 1 to 10 dB in OCT imaging of human rectum ex vivo. Results of ex vivo studies are in good agreement with Monte Carlo simulations. Application of pressure of 0.45 N/mm2 causes increase in contrast of epidermis-dermis junction in OCT-images of human skin in vivo for about 10 dB.
展开▼
机译：讨论了在施加机械压缩之后的OCT图像中的生物筛片层对比。该研究进行了人体直肠的前体内样本，体内进行人类志愿者的皮肤。我们表明，由于层的不同机械性能，机械压缩提供了生物化层边界的对比度。我们表明，从0.45n / mm 2的压力的改变导致人体直肠离体的10月成像的1至10dB的对比度增加。前体内研究的结果与Monte Carlo模拟有关。 0.45n / mm2的压力的施用导致表皮-Dermis结的对比度增加了体内人体皮肤的OCT图像约10dB。
展开▼
