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Intra- and inter-frame differential Doppler imaging

机译:帧内帧间差分多普勒成像

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We present a method to contrast the blood flow of retinal vessels from the surrounding static tissue. It is based on the extinction of the interference fringes by phase shifts of π. If moving particles within the sample introduce an additional phase shift, the signal from these particles will, in contrast to the signal from static tissue, not be attenuated. We demonstrate different variants of this method, where we introduce phase shifts during single A-scans, consecutive A-scans and consecutive B-scans. We show proof-of-principle measurements with a piezo mirror, as well as in-vivo measurements of the human retina for the different phase shifting schemes. We demonstrate its capability to contrast a wide range of perfused retinal vessels; from large vessels present in the optic nerve head region to the capillary network surrounding the fovea.
机译:我们提出了一种对与周围静态组织的视网膜血管血流对比的方法。它基于干扰条纹的偏移通过π的相移。如果样品内的移动颗粒引入另外的相移,则来自这些颗粒的信号与来自静态组织的信号相反,不衰减。我们展示了这种方法的不同变体,其中我们在单个A扫描期间引入相移,连续的A扫描和连续B扫描。我们用压电镜显示原理上的原理测量,以及用于不同相移方案的人视网膜的体内测量。我们展示了它的能力与较宽的灌注视网膜造影;从视神经顶部区域中存在的大容器到围绕FOVEA的毛细管网络。

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