Morphometric Studies of first-episode schizophrenia's brain structures

摘要

Many studies have already demonstrated structural brain differences among different patient populations using the morphometric analysis techniques. Voxel-based morphometry (VBM) and deformation-based morphometry (DBM) are the two widely used methods. This paper mainly compared the difference of the two methods and analyzed the reason why many differences exist in the experimental results focused on the same disease. The first-episode schizophrenia's brain structures were analyzed using both VBM and DBM. The results based on the two methods exactly evaluated our analysis and provided pathological evidence for the first-episode schizophrenia.