Pathogenetic types of rheological disturbances in patients with stroke

摘要

A total of 136 men (48.2+2.14 years), stroke, mainly in the subacute and residual periods. Studied electrical and viscoelastic parameters of erythrocytes by dielectro-phoresis, hemostasis, phosphorus compounds erythrocytes by 31P NMR spectroscopy. Identified various options for rheological disturbances may underlie the pathogenesis of various forms of stroke. For the first subgroup of patients with elements of the metabolic syndrome is characterized by marked disturbances of deformability of red blood cells, predisposing to the development of microcirculatory disorders with a distinct lack of intracellular macroergastic compounds. For the second subgroup of patients without traditional risk factors - hypertension and hyperlipidemia is characteristic damage to the membranes (with the possible participation of viral infection) with increased hemolysis of red blood cells, predisposing to abnormal aggregation and thrombosis.