A method for rapid simulation of propagating wave fronts in three-dimensional cardiac muscle with spatially-varying fiber orientations

摘要

We describe a simple cellular automata model for cardiac electrical activation that can simulate propagation in 3D muscle with arbitrary local fiber orientations. The model is computationally efficient and can provide activation sequences for rapidly driving models of cardiac mechanics. Here we show how to compute the model parameters from tissue parameters and successfully demonstrate rapid simulation of wave fronts in a slab of tissue with a rotating fiber structure.