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Blood vessel segmentation in digital subtraction angiograms

机译:数字减法血管仪中的血管分割

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The growing use of digital medical imaging gives rise to the question of data archiving and retrieval. Dedicated applications, i.e. telemedicine and image exchange impose severe demands on networking and storage resources. This bottleneck can be moderated using content-orientated image compression which reduces the amount of data while preserving the diagnostic information. This paper presents an new method for automated vessel segmentation which can be used for both, decision support systems and content-orientated image compression of angiograms. Some vasculature detection approaches use differentiating operators which are problematic since they are not immune to the usually high noise level in angiograms. Histogram segmentation ignore most of the knowledge of vessel geometry. Tracking approaches with matched filters are favored here, because they do not possess the above mentioned disadvantages. However, they depend largely on exact signal and noise models, which has not been exhaustively investigated so far. In this article, an accurate vascular model is derived from angiographic imaging equations. The anatomical knowledge of blood vessels can be better exploited using a Kalman filter, which uses an explicit vessel model. This optimizing filter has an additional advantage: Some heuristic thresholds of the tracking process can be optimized with respect to sample data. A further problem is the evaluation of the detected vasculature, which is of prime importance in medical applications. Here, a new automated structural evaluation method of vessel trees by means of graph matching is presented. Tests of the new method showed very good results, also very small and hardly recognizable vessels have been detected. The structural check shows that some errors like oversegmentations can be discovered using structural knowledge.
机译:越来越多的数字医学成像的使用引起了数据归档和检索的问题。专用应用程序,即远程医疗和图像交流对网络和存储资源产生严重的要求。可以使用面向内容的图像压缩来调节该瓶颈,这减少了保留诊断信息时的数据量。本文介绍了一种用于自动血管分割的新方法,可用于血管造影的决策支持系统和面向内容的图像压缩。一些血管系统检测方法使用鉴别的操作员,这是有问题的,因为它们不会对血管造影中的通常高噪声水平免疫。直方图分割忽略大多数血管几何形状的知识。跟踪具有匹配过滤器的方法在此处受到青睐,因为它们没有上述缺点。然而,它们主要取决于到目前为止没有详尽调查的精确信号和噪声模型。在本文中,精确的血管模型来自血管造影成像方程。使用具有显式船舶模型的卡尔曼滤波器,可以更好地利用血管的解剖学知识。此优化过滤器具有一个额外的优点:追踪处理的一些启发式阈值可以相对于样本数据进行优化。另一个问题是评估检测到的脉管系统,这在医学应用中具有重要性。这里,提出了一种通过图形匹配的血管树的新的自动结构评估方法。新方法的测试显示出非常好的结果,也检测到非常小的且难以识别的血管。结构检查表明,可以使用结构知识发现一些类似的错误。

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