Laser-induced fluorescence spectroscopy of human normal and cancerous tissues

摘要

Fluorescence properties of stomach tissues have been investigated to determine whether malignant specimens can be discriminated in vitro. Differences between normal and tumor tissues are found that concern both the intensity distribution and spectral shape of the autofluorescence emission. According to the distinctions tumor tissues would be differed from the normal tissues. The resulting spectra could be differentiate histologically stomach abnormal tissues from normal tissues with a sensitivity and specificity value of 90 percent and 92 percent. Furthermore, fluorescence spectra from human stomach normal and malignant tissues have been measured in real time in vivo.