A fluorescence-detection technique for cancer in human hollow organs has been developed based on endoscope-assisted two-wavelength excitation of the polyporphyrin Photofrin II in tissue. Due to the photosensitizing capability of the fluorescent tumormarket the applied dose is reduced to 0.4 mg/kg bw which avoids photosensitization of the patient's skin. Fluorescence is detected either spectrally resolved by means of an optical multichannel analyzer or by imaging of diseased tissue areas with an intensified video system. The fluorescence pattern in the final image is presented with high contrast due to realtime subtraction of nonspecific background signals.
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机译：基于组织中的多肽光rin II的内窥镜辅助的双波长激发，开发了人中空器官中癌症的荧光检测技术。由于荧光Tumormarket的光敏能力，施用剂量降低至0.4mg / kg Bw，避免了患者皮肤的光敏。通过光学多通道分析仪检测荧光光谱分解或通过用强化视频系统成像患病的组织区域。由于非特异性背景信号的实时减法，最终图像中的荧光模式具有高对比度。
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