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Full-range spectral domain Doppler optical coherence tomography

机译:全范围光谱域多普勒光学相干断层扫描

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Spectral domain optical coherence tomography (SD-OCT) systems achieve higher sensitivities compared to time domain OCT systems. However, one of the main challenges in SD-OCT is the obscuring object structure called "ghost image" or "mirror image" that arises from the Fourier transform of a real function. We have designed and developed a phase-shifting-based full-range SD-OCT system that we refer to as the dual detection full range SD-OCT. The proposed technique simultaneously obtains the quadrature components of a complex spectral interference. Therefore, the technique enables full range imaging without any loss of speed and is intrinsically less sensitive to movements of the subject. In this paper, we demonstrate that the dual detection technique can be applied to Doppler imaging without loss in the velocity dynamic range since the phase information of the acquired spectra is preserved. The dual detection full range SD-OCT provides a superior signal-to-noise ratio over a conventional SD-OCT since the most sensitive region around the zero path delay is usable. This capability improves the image quality of not only the structural image but also the Doppler image.
机译:与时域OCT系统相比,光谱域光学相干断层扫描(SD-OCT)系统实现更高的灵敏度。然而,SD-OCT中的主要挑战之一是暗示了来自真实功能的傅里叶变换的“幽灵图像”或“镜像”的遮蔽物结构。我们设计并开发了一种基于逐步的全范围SD-OCT系统,我们称为双重检测全范围SD-OCT。所提出的技术同时获得复杂光谱干扰的正交分量。因此,该技术使得全系数成像能够无需任何速度损失并且本质上对受试者的运动敏感。在本文中,我们证明了双重检测技术可以应用于多普勒成像,而不会在速度动态范围内损失,因为所获取的光谱的相位信息被保留。自零路径延迟周围最敏感的区域是可用的,双检测全范围SD-OCT通过传统的SD-OCT提供卓越的信噪比。这种能力不仅可以改善结构图像的图像质量,而且改善了多普勒图像。

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