Mesenchymal Stem Cell Response to Covalent Functionalized Recombinant Fibronectin Fragments onto New Titanium-Niobium-Hafnium Alloy

摘要

The modification of Ti biomechanical properties using the combination of metal alloying and ECM recombinant fragments functionalization seems promising for bone substitution purposes. In vitro results suggested that combinations of CAS and HB2 recombinant fragments were better for cellular adhesion quality, proliferation and differentiation responses than single fragments, obtaining interesting results for 70%CAS-30%HB2 combination.