A Non-Gaussian LCMV beamformer for MEG Source Reconstruction

摘要

Evidence suggests that magnetoencephalogram (MEG) data have characteristics with non-Gaussian distribution, however, standard methods for source localisation assume Gaussian behaviour. We present a new general method for non-Gaussian source estimation of stationary signals for localising brain activity in the MEG data. By providing a Bayesian formulation for linearly constraint minimum variance (LCMV) beamformer, we extend this approach and show that how the source probability density function (pdf), which is not necessarily Gaussian, can be estimated. The proposed non-Gaussian beamformer is shown to give better spatial estimates than the LCMV beamformer, in both simulations incorporating non-Gaussian signal and in real MEG measurements.