Keynote: THERAPEUTIC DRUG MONITORING AND DRUG DISCOVERY: IS IT ALL KNOWN OR ARE WE INNOVATIVE AND GAME CHANGING?

摘要

Nowadays, mass spectrometry, mostly hyphenated with either GC or LC, is THE prime technology applied in therapeutic drug monitoring (TDM) and drug discovery (DD). The accurate quantitation of drugs and related metabolites are essential for personalized treatment scenario's in the clinic, while both quantitative and qualitative data of these drugs and associated metabolites or PD effects are required in drug discovery.