AN OVERVIEW OF STUDIES ON THE RELATIONSHIP BETWEEN INDOOR COAL BURNING AND LUNG CANCER

摘要

In Xuan Wei county, Yunnan province, lung cancer mortality rate was China's highest. To study the main risk factors for lung cancer in Xuan Wei with special reference to indoor coal burning, we conducted a multidisciplinary research. The results consistently showed that the main risk factor for the increase in lung cancer mortality in Xuan Wei was the exposure to indoor air pollution from smoky coal emissions that contain high levels of polycyclic aromatic hydrocarbons (PAH). The association between the exposure and lung cancer risk might be increased by GSTM1 null genotype as well as overexertion of the P53 protein.