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DRY AND CRUSTY NASAL MUCOSA AS A SIGN OF INCREASED SENSITMTY TO ENVIRONMENTAL POLLUTION

机译:干燥和硬皮鼻腔粘膜作为对环境污染的敏感性增加的标志

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Exposure to irritating pollutants make some people react with nasal symptoms and asthma, even if traditional clinical tests show no remarkable values. To extend the study of this, data from a prospective study of teachers in a renovated, earlier moisture damaged school and a control school without moisture problems were used. 28 teachers from the target school and 18 teachers from the control school were examined rhinoscopically and thereafter exposed to a nasal histamine provocation test. The rhinoscopic examination of all teachers showed that 15 subjects had a dry and crusty mucosal appearance and 31 did not. The prevalence of this rhinoscopic finding was similar in both schools. Those with a dry and crusty appearance reacted significantly more in the histamine provocation test compared to the other teachers (p=0.0004). The teachers with a rhinoscopically dry and crusty mucosal appearance complained more frequently about skin symptoms (53 % and 7%, respectively, p< 0.01) and reported somewhat more irritative mucosal symptoms (33% and 16% respectively) than those without this appearance In conclusion a similar prevalence of teachers with dry and crusty nasal membranes in both the target and the control school, might indicate a constitutional factor and the existence of a subgroup in the total population,reacting more strongly to environmental factors.
机译:暴露于刺激性污染物使有些人也与鼻症状和哮喘反应,即使传统的临床测试没有显着的价值观。为了延长这一点,使用了在经过翻新的,早期水分损坏的学校和一个没有水分问题的控制学校的教师前瞻性研究的数据。来自目标学校的28名教师和来自对照学校的18名教师在脑镜下检查,然后暴露于鼻组胺挑衅试验。所有教师对所有教师的校验审查表明,15名受试者的粘膜外观,31例没有。这两所学校的鉴赏者发现的患病率相似。与其他教师相比,具有干燥和硬皮外观的那些在组胺挑衅试验中产生显着更高(P = 0.0004)。具有犀鸟干燥和耐粘膜外观的教师抱怨皮肤症状(分别为53%和7%,P <0.01),并报告了比没有这种外观的情况更多的刺激性粘膜症状(分别为33%和16%)结论在目标和对照学校的干燥和硬皮鼻膜中具有类似教师的普遍性,可能表明宪法因素和亚组的存在在总人口中,对环境因素更强烈地反应。

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