USEFULNESS OF CULTURED SKIN TYPED PATCH CONTAINING TETRACYCLINE HCL AND CHLORAMPHENICOL: MATHEMATICAL APPROACH

摘要

Cultured skin containing antibiotics was prepared and applied on the wounded hairless rat skin. The resulting permeation profile of antibiotics was mathematically evaluated to calculate the drug level in the wounded tissue. The obtained data suggest that the present system must be a new DDS for the treatment of burns.