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Atrial Fibrillation Surgical Ablation Long-term Outcome Prediction Just with One Lead of the Preoperative Surface Electrocardiogram

机译:心房颤动的手术消融的长期结果预测只有一端术前表面心电图

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To revert atrial fibrillation (AF) in patients requiring concomitant open-heart surgery, surgical ablation (SA) is one of the most effective procedures. However, this intervention is as- sociated with major side effects. Considering this limitation together with the benefits of anticipating antiarrhythmic treatment decisions, preoperative prediction of long-term outcome of SA is an interesting challenge. In the present work a novel algorithm to anticipate SA outcome after a follow-up of 12 months is introduced by just analyzing one lead from a preoperative electrocardiogram (ECG). Precisely, fibrillatory waves reflected on lead V1 are extracted using a QRST cancellation method. The obtained signal is divided into 1 s-length segments, which are decomposed into 8 time scales by making use a Wavelet transform. Finally, relative wavelet energy for each segment and scale is computed and the standard deviation of the time series for the 7th scale is obtained as a measure of organization of the fibrillatory waves. This index obtained statistically significant differences between the patients who maintained sinus rhythm and relapsed to AF during the follow-up. Moreover, it also yielded a discriminant ability about 75%, thus improving between 13 and 29% the one showed by other well-established parameters.
机译:为了回避需要伴随露天手术的患者的心房颤动(AF),手术消融(SA)是最有效的程序之一。但是,这种干预与主要副作用相同。考虑到这种限制以及预期抗心律失常治疗决策的益处,术前预测SA的长期结果是一个有趣的挑战。在目前的工作中,通过从术前心电图(ECG)中,通过分析一个引线来预测在12个月后续12个月后预测SA结果的新算法。精确地,使用QRST消除方法提取反映在引线V1上的原纤化波。将所得信号分成1个S长段,通过使用小波变换来分解成8个时间尺度。最后,计算每个段和比例的相对小波能量,并且获得第七尺度的时间序列的标准偏差作为纤维化波的组织的量度。该指数在维持窦性心律并在随访期间复发到AF之间的患者之间获得统计学显着差异。此外,它还产生了约75%的判别能力,从而改善了其他良好建立的参数的13至29%。

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