Multi-spectral vascular oximetry of rat dorsal spinal cord

摘要

We describe a visible-light multi-spectral system for vascular oximetry studies that can be implemented in low-and middle-income countries, using a low-cost electronics and optical elements, for instance a Raspberry Pi, aPi camera under a resolution of 5-megapixel, and four light sources at 480nm, 532nm, 593nm and 610nm. Itis designed to quantify the vascular oxygen saturation of the rat dorsal spinal cord, Python custom applicationsynchronizes all elements to execute the imaging process in one system. The device is suitable offers a replacementfor high cost bulky systems in drug discovery, tracking disease progression and understanding of progressive anddegenerative diseases.