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Health Effects of Exposure to Non-Tailpipe PM Emissions: A Critical Review

机译:暴露于非尾气颗粒物排放对健康的影响:一项重要评论

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Gerard Hoek Background: Because of the reduction of tailpipe particulate emissions in most-high income countries, the relative importance of non-tailpipe emissions of motor vehicles is increasing. Epidemiological studies have started to study non-tailpipe emissions specifically. In this presentation, I will review epidemiological studies that have specifically assessed non-tailpipe emissions, separate from exhaust emissions. Methods: Epidemiological studies were identified by a search in Medline. Studies assessing mortality and morbidity endpoints were eligible. We included time series, case-crossover assessing short-term effects and cohort studies assessing long-term exposures. Results: We identified a fairly large number of time series studies on measured elemental composition and mortality / hospital admissions, predominantly in the USA. A small number of (birth and adult) cohort studies was identified where exposure was assessed with land use regression of elemental composition, including the European ESCAPE study. In some studies, Cu, Fe or Zn in PM were associated with adverse health effects, but in other studies no association was found. In most studies that evaluated markers of tailpipe emissions such as N02 or Black carbon, the correlation with these markers was high. Conclusions: Epidemiological studies on short and long term exposure to non-tailpipe emissions have generally not been fully consistent. Reasons for inconsistencies across studies included limitations in exposure assessment and the challenge of separating non-tailpipe from tailpipe emissions effects.
机译:Gerard Hoek背景:由于大多数高收入国家的尾气颗粒排放减少,机动车辆的非尾管排放的相对重要性正在增加。流行病学研究已经开始具体研究非尾管排放。在本演示文稿中,我将审查专门评估非尾管排放的流行病学研究,与废气排放分开。方法:通过在Medline中搜索鉴定流行病学研究。评估死亡率和发病率终点的研究有资格。我们包括时间序列,案例交叉评估短期效应和群组研究评估长期曝光。结果:我们确定了关于测量元素组成和死亡率/医院入学的相当大的时间序列研究,主要是在美国。鉴定了少数(出生和成人的)队列研究,其中通过欧洲逃生研究在内的元素组成的土地利用回归评估了暴露。在一些研究中,PM中的Cu,Fe或Zn与不良健康影响有关,但在其他研究中,没有发现任何关联。在大多数研究中,评估尾管排放量的标记,例如N02或黑碳,与这些标记的相关性高。结论:对非尾管排放的短期和长期暴露的流行病学研究通常并未完全一致。跨研究不一致的原因包括暴露评估的限制以及将非尾管与尾管排放效应分离的挑战。

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