Effect of homogeneous and inhomogeneous high magnetic fields onbacterial growth measured under a newly developed superconducting magnetbiosystem

摘要

A new superconducting magnet biosystem (SBS) was developed whichcan provide 0.5 to 7 tesla (T) magnetic fields. The aerobic growth of abacterium, Bacillus subtilis M1113 was investigated under homogeneous 7T and inhomogeneous 5.2-6.1 T magnetic fields in SBS. In the stationaryphase, the cell number under the magnetic field was about 2 times higherthan that of a control, indicating that the high magnetic field inhibitsthe death rate of bacterial cells. A genetically transformed B. SubtilisM1113 (pC112) produced higher concentration of a lipopeptide antibiotic,surfactin, under a high magnetic field, reflecting higher cell numbersunder a high magnetic field compared with that in the geomagnetic field