In this paper, beam-shifting optical coherence tomography (BSOCT) is presented for speckle reduction and flow ratemeasurement. The sample beam is rotated about the optical axis of the objective lens to modulate the incident angle onsample; 17 and 3 incident angles are respectively performed for speckle reduction and flow rate measurement. Theperformance of the proposed technique is investigated on both phantom and in vivo experiments. By combining a 2Dmicro-electro-mechanical system (MEMS) and a zigzag scanning protocol, the frame rates of 45.2 Hz for specklereduction and 25.6 Hz for flow rate measurement are achieved. With beam-shifting angle of 4.76º, the speckle noisereduction of 91% and the flow rate measurement precision of 0.0019 μl/s are achieved.
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