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Simulation of laser induced retinal thermal injuries for non-uniform irradiance profiles and their evaluation according to the laser safety standard

机译:激光辐照性视网膜热损伤非均匀辐照曲线的模拟及其根据激光安全标准的评估

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Laser systems emitting radiation in the visible and near infrared region arc potentially hazardous for the retina of the human eye. This can result in irreparable injuries due to photomechanical, photothcrmal or photochemical light-tissue interactions. This investigation focuses on the photothermal interaction for which a computer model is used to simulate the thermal behavior of the retina and to predict the injury threshold values. The most important factors are the wavelength of the radiation, the exposure time and the irradiance profile on the retina. For performing safety evaluations and classifications the laser safety standard IEC 60825-1:2014 has to be considered. These evaluations arc based on emission limits which depend on the same above mentioned factors. According to the IEC 60825-1:2014, non-uniform retinal images are treated by an image analysis where an averaged spot size is used. This averaged size is calculated by the extent of the irradiance profile along two orthogonal directions. Unlike the laser safety standard, the computer model predicts the injury thresholds for an irradiance profile on the retina without averaging the spot size. In this investigation, a broad variety of non-uniform retinal images is investigated with regard to the injury thresholds predicted by the computer model and to the classifications according to the laser safety standard.
机译:在可见光和近红外区域发射辐射的激光系统可能会对人眼的视网膜造成危害。由于光机械,光热或光化学的光组织相互作用,可能导致无法挽回的伤害。这项研究的重点是光热相互作用,为此使用计算机模型来模拟视网膜的热行为并预测损伤阈值。最重要的因素是辐射的波长,曝光时间和视网膜上的辐照度分布。为了进行安全评估和分类,必须考虑激光安全标准IEC 60825-1:2014。这些评估基于排放限值,该限值取决于上述相同因素。根据IEC 60825-1:2014,通过使用平均光斑大小的图像分析来处理非均匀性视网膜图像。该平均尺寸是通过沿两个正交方向的辐照度分布范围来计算的。与激光安全标准不同,计算机模型可以预测视网膜上的辐照度轮廓的伤害阈值,而无需平均光斑大小。在这项研究中,针对计算机模型预测的损伤阈值以及根据激光安全标准进行的分类,研究了各种各样的视网膜不均匀图像。

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