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Heating Patterns in Patient Body by Capacitive Heating Device Using 8 MHz Radio Frequency Current

机译:通过使用8 MHz射频电流的电容加热装置加热患者体内的加热图案

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In recent years, various types of medical applications of electromagnetic techniques have been investigated. Especially, thermal effect of the electromagnetic field to human body can be used for treatment of cancer. Today, large number of capacitive heating devices, which utilize electric current of 8 MHz, are employed in Japan. In the device, electric current of 8 MHz is applied to a patient via pair of electrodes. Temperature of target tumor(s) inside the patient and their periphery elevated by Joule heating of the current. The temperature in and around the target can be measured by some thermocouples equipped with the device. However, the temperatures are not measured in many cases because of invasiveness. So, in this study, the temperatures inside the body were calculated under practical situation. In this study, realistic high resolution whole body voxel model [1] developed by National Institute Information and Communications Technology (NICT, Tokyo, Japan) is employed as a patient under the thermal treatment. The patient is placed between two electrodes, whose diameter is 250 mm, with water boluses. In the calculation, first, specific absorption rate (SAR) is calculated by use of finite difference time domain (FDTD) method. Then, the bioheat transfer equation is numerically solved based on the resultant SAR values with several practical parameters. From the calculated result, some high temperature regions are observed around the surface of the patient body. On the other hand, the temperature of deep region of the body such as some organs are not increased compared with the surface. In addition, a patient model whose liver includes spherical tumor region has been calculated. Here, the tumor is a low blood flow region. In this case, temperature elevation can be observed at the tumor region because of low cooling effect by the blood flow. As a further study, many treatment cases should be considered for understanding the characteristics of the capacitive heating scheme.
机译:近年来,已经研究了各种类型的电磁技术医学应用。特别地,电磁场对人体的热效果可用于治疗癌症。如今,利用8 MHz电流的大量电容加热装置在日本采用。在该装置中,通过一对电极将8MHz的电流施加到患者。患者内部靶肿瘤的温度及其周边通过电流的焦耳加热升高。目标内和周围的温度可以通过配备有装置的一些热电偶来测量。然而,由于侵袭性,在许多情况下没有测量温度。因此,在本研究中,在实际情况下计算体内的温度。在这项研究中,由国家学院信息和通信技术(NICT,东京,日本)开发的现实高分辨率全身体素模型[1]作为患者作为热处理的患者。患者置于两个电极之间,其直径为250mm,用水缩进。在计算中,首先,通过使用有限差分时域(FDTD)方法计算特定的吸收率(SAR)。然后,基于具有若干实际参数的所得的SAR值来数量求解生物发热方程。根据计算结果,在患者体的表面周围观察到一些高温区域。另一方面,与表面相比,诸如某些器官的身体深区域的温度不会增加。另外,已经计算了肝脏包括球形肿瘤区域的患者模型。这里,肿瘤是低血流区域。在这种情况下,由于血流冷却效果低,可以在肿瘤区域观察到温度升高。作为进一步的研究,应考虑许多治疗案例来理解电容式加热方案的特性。

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