We are delighted to present the proceedings of the 16th International Conference on Ontologies, DataBases, and Applications of Semantics (ODBASE) which was held in Rhodes (Greece) 24-25 October 2017. The ODBASE Conference series provides a forum for research and practitioners on the use of ontologies and data semantics in novel applications, and continues to draw a highly diverse body of researchers and practitioners. ODBASE is part of the OnTheMove (OTM 2017) federated event composed of three interrelated yet complementary scientific conferences that together attempt to span a relevant range of the advanced research on, and cutting-edge development and application of, information handling and systems in the wider current context of ubiquitous distributed computing. The other two co-located conferences are CoopIS'17 (Cooperative Information Systems) and C&TC'17 (Cloud and Trusted Computing). Of particular relevance to ODBASE 2017 are papers that bridge traditional boundaries between disciplines such as artificial intelligence and Semantic Web, databases, data analytics and machine learning, social networks, distributed and mobile systems, information retrieval, knowledge discovery, and computational linguistics.
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