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Electroactive polymers for healthcare and biomedical applications

机译:用于医疗保健和生物医学应用的电活性聚合物

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Electroactivity was noticed early in biological substances, including proteins, polynucleotides and enzymes, even piezo-and pyroelectricity were found in wool, hair, wood, bone and tendon. Recently, ferroelectricity has been identified in a surprisingly large number of biologically relevant materials, including hydroxyapatite, aortic walls and elastin. Inspired by the variety of natural electroactive materials, a wealth of new elastomers and polymers were designed recently, including an all organic elastomer electret and self-healing dielectric elastomers. Let's further draw inspiration from nature and widen the utilization of electroactive polymers towards (mobile) healthcare and biomedical applications. Ferroelectrets, internally charged polymer foams with a strong piezoelectric thickness coefficient are employed in biomedical sensing, for example as blood pressure and pulse sensor, as vital signs monitor or for the detection of tonic-clonic seizures. Piezo- and pyroelectric polymers are booming in printed electronics research. They provide electronic skin the ability to "feel" pressure and temperature changes, or to generate electrical energy from vibrations and motions, even from contractile and relaxation motions of the heart and lung. Dielectric elastomers are pioneered by StretchSense as wearable motion capture sensors, monitoring pressure, stretch, bend and shear, quantifying comfort in sports and healthcare. On the cellular level, electroactive polymer arrays are used to study mechanotransduction of individual cells. Ionic electroactive polymers show potential to be used in implantable electroactive biomedical devices. Already with the currently available science and technology, we are at the verge of witnessing the demonstration of truly complex bionic systems.
机译:在包括蛋白质,多核苷酸和酶在内的生物物质中,很早就注意到了电活性,甚至在羊毛,头发,木材,骨骼和肌腱中也发现了压电和热电性。近来,已经在令人惊讶地大量的生物相关材料中鉴定出铁电,所述材料包括羟基磷灰石,主动脉壁和弹性蛋白。受各种天然电活性材料的启发,最近设计了许多新的弹性体和聚合物,包括全有机弹性体驻极体和自修复介电弹性体。让我们进一步从自然界中汲取灵感,并扩大电活性聚合物在(移动)医疗保健和生物医学领域的应用。铁电驻极体,内部填充的具有强压电厚度系数的聚合物泡沫被用于生物医学传感中,例如用作血压和脉搏传感器,作为生命体征监测器或用于检测强直-阵挛性癫痫发作。压电和热电聚合物在印刷电子学研究中正在蓬勃发展。它们使电子皮肤能够“感觉”到压力和温度的变化,或者通过振动和运动,甚至通过心脏和肺部的收缩运动和松弛运动来产生电能。介电弹性体是StretchSense最早开发的可穿戴运动捕捉传感器,可监测压力,拉伸,弯曲和剪切,从而量化运动和医疗保健的舒适度。在细胞水平上,电活性聚合物阵列用于研究单个细胞的机械转导。离子电活性聚合物显示出可用于植入式电活性生物医学设备的潜力。借助当前可用的科学技术,我们正处于见证真正复杂的仿生系统演示的边缘。

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