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DAGSENS: Directed acyclic graph based direct and adjoint transient sensitivity analysis for event-driven objective functions

机译:DAGSENS:基于有向无环图的基于直接和伴随瞬态灵敏度分析的事件驱动目标函数

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We present DAGSENS, a new approach to parametric transient sensitivity analysis of Differential Algebraic Equation systems (DAEs), such as SPICE-level circuits. The key ideas behind DAGSENS are, (1) to represent the entire sequence of computations from DAE parameters to the objective function (whose sensitivity is needed) as a Directed Acyclic Graph (DAG) called the “sensitivity DAG”, and (2) to compute the required sensitivites efficiently by using dynamic programming techniques to traverse the DAG. DAGSENS is simple, elegant, and easy-to-understand compared to previous approaches; for example, in DAGSENS, one can switch between direct and adjoint sensitivities simply by reversing the direction of DAG traversal. Also, DAGSENS is more powerful than previous approaches because it works for a more general class of objective functions, including those based on “events” that occur during a transient simulation (e.g., a node voltage crossing a threshold, a phase-locked loop (PLL) achieving lock, a circuit signal reaching its maximum/minimum value, etc.). In this paper, we demonstrate DAGSENS on several electronic and biological applications, including high-speed communication, statistical cell library characterization, and gene expression.
机译:我们介绍了DAGSENS,这是一种新的方法,用于分析微分代数方程组(DAE)(例如SPICE级电路)的参数瞬态灵敏度。 DAGSENS背后的关键思想是:(1)以称为“灵敏度DAG”的有向无环图(DAG)表示从DAE参数到目标函数(需要其灵敏度)的整个计算序列,以及(2)通过使用动态编程技术遍历DAG,可以有效地计算所需的敏感度。与以前的方法相比,DAGSENS是简单,优雅且易于理解的。例如,在DAGSENS中,只需简单地反转DAG遍历的方向即可在直接灵敏度和伴随灵敏度之间切换。同样,DAGSENS比以前的方法更强大,因为它可用于更通用的目标函数,包括基于瞬态仿真过程中发生的“事件”的目标函数(例如,节点电压超过阈值,锁相环( PLL)达到锁定,电路信号达到其最大值/最小值等)。在本文中,我们演示了DAGSENS在多种电子和生物学应用中的应用,包括高速通信,统计细胞文库表征和基因表达。

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