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Enabling atrial fibrillation detection using a weight scale

机译:使用体重秤启用房颤检测

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Atrial fibrillation (AF) is a cardiac arrhythmia characterized by a highly irregular heart rate. It is the most prevalent arrhythmia in the general population in the United States and most developed countries, and is strongly associated with increased morbidity and mortality from adverse cardiovascular and cerebrovascular events. Moreover, patients with AF are correlated with increased healthcare expenditures, making the burden of AF on society extremely large. In this proof-of-concept study, we present an innovative device to be used as a screening tool for AF. The device consists of a modified electronic scale that is able to obtain an ECG and analyse it for the presence of AF. The classification algorithm is based on the RdR map method that plots RR intervals versus change in RR intervals. After optimizing the algorithm on a learning set of 77 ECGs from 45 patients, the performance of the device during a blind validation of 76 ECGs from 44 patients was: accuracy = 83%, sensitivity = 83%, specificity = 83% (N = 76 ECGs). Applying a constraint that each ECG recording contains a minimum of 7 beats in order to be eligible for classification, accuracy improved to 89% (sensitivity = 83%, specificity = 90%, N = 70). In conclusion, we present an innovative device to detect AF in a manner that can be implemented into current physician workflow without increasing the time or cost of each clinical encounter.
机译:心房颤动(AF)是一种心律不齐,其特征是心律高度不规则。它是美国和大多数发达国家中最普遍的心律失常,与心血管和脑血管不良事件的发病率和死亡率增加密切相关。此外,患有AF的患者与增加的医疗保健支出相关,这使得AF对社会的负担非常大。在此概念验证研究中,我们提出了一种创新的设备,可用作AF的筛查工具。该设备包含一个经过修改的电子秤,该电子秤能够获取ECG并分析其是否存在AF。分类算法基于RdR映射方法,该方法绘制了RR间隔与RR间隔的变化之间的关系。在对来自45位患者的77个ECG的学习集上优化算法后,在对44位患者的76个ECG进行盲确认期间,该设备的性能为:准确度= 83%,灵敏度= 83%,特异性= 83%(N = 76心电图)。施加一个约束,即每个ECG记录至少包含7个搏动才能符合分类要求,准确度提高到89%(灵敏度= 83%,特异性= 90%,N = 70)。总之,我们提出了一种创新的设备,可以以一种可以在当前医师工作流程中实施的方式检测房颤,而不会增加每次临床诊治的时间或成本。

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