Single strand DNA detection by means of lossy mode resonance-based optical fiber devices

摘要

DNA sequence detection has a broad range of applications in different fields such as genetics, pathology, criminology, pharmacogenetics, public health, food safety, agriculture, defense and environmental monitoring. However, common DNA detection techniques present several drawbacks such as bulky size, restricted to laboratory environments, high equipment cost and time consuming experiments. Here, we present an alternative DNA detection technique by means of the utilization of label-free lossy mode resonance (LMR) based optical fiber refractometers and compare two different DNA immobilization techniques.