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Optically controlled design of bi-functional agents for development of competitive immunoassays of enhanced sensitivity

机译:用于发展增强敏感性的竞争免疫测定的双功能试剂的光学控制设计

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摘要

Label-free approach is developed based on the spectral-correlation and spectral-phase interferometric methods for characterization and fine-tuning of bi-functional ligands, which can improve the limits of detection of immunoassays by several orders of magnitude. The concept was verified by development and optimization of an ultrasensitive test system for registration of thyroxine (a marker of thyroid diseases).
机译:基于光谱相关和光谱相干涉方法开发了无标记方法,用于双官能配体的表征和微调,可以通过几个数量级来改善免疫测量的限制。通过用于登记甲状腺素(甲状腺疾病的标志物)的超敏感测试系统的开发和优化验证了该概念。

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