Modern medicine has the potential of becoming both more personalized-and low cost-thanks to recent discoveries at the intersection of molecular biology, chemistry, and engineering physics. I will speak about using optical controls of our individual gene circuits in living cells for the treatment of cancer, infectious diseases and neurological diseases. I will also describe an integrated molecular diagnostic system, which, with the help of cell phones and GPS, will enable epidemiological surveying and remote healthcare delivery. These are just two examples of new solutions made possible by bionanoscience to some of the greatest challenges in global healthcare. I will share my vision of BIGHEART, which requires the convergence of integrative art, culture, and technology and science (iACTS). The BIGHEART with iACTS can solve ill-defined real-world problems of global healthcare in both developed and developing world.
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