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High performance microstructured Lu_2O_3: Eu thin film scintillator for X-ray computed tomography

机译:用于X射线计算机断层扫描的高性能微结构Lu_2O_3:Eu薄膜闪烁器

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Large penetration depth and weak interaction of high energy X-rays in living organisms provide a non-destructive way to study entire volumes of organs without the need for sophisticated preparation (injection of contrast material, radiotracer labels etc.). X-ray computed tomography (CT) is a powerful diagnostic tool allowing 3D image reconstruction of the complete structure. Using hard X-rays in medical imaging leads to reduced dose received by the patient. At higher energies, however, the conventional scintillators quickly become the limiting factor. They must be thin in order to provide reasonable spatial resolution and preserve image quality. Nevertheless, insufficient thickness introduces the need for long acquisition times due to low stopping power. To address these issues, we synthesized a new structured scintillator to be integrated into CCD- or photodiode-based CT systems. Europium-doped Lu_2O_3 (Lu_2O_3:Eu) has the highest density among all known scintillators, very high absorption coefficient for X-rays and a bright red emission matching well to the quantum efficiency of the underlying CCD- and photodiode arrays. When coupled to a suitable detector, this microcolumnar scintillator significantly improves the overall detective quantum efficiency of the detector. For the first time ever, structured and scintillating film of Lu_2O_3:Eu was grown by electron-beam physical vapor deposition. A prototype sensor was produced and evaluated using both laboratory X-ray sources as well as synchrotron radiation. Comparative performance evaluations of the newly developed sensor versus commercial grade scintillators were conducted. Such synthesis of high density, micro-structured, scintillating coatings enables the development of high sensitivity X-ray detectors for CT applications.
机译:生物体中高能量X射线的大型渗透深度和弱相互作用提供了一种非破坏性的方法来研究整个体积的器官,而无需复杂的制剂(注射造影材料,放射性物质标记等)。 X射线计算机断层扫描(CT)是一种强大的诊断工具,允许完整结构的3D图像重建。使用医学成像中的硬X射线导致患者接收的剂量减少。然而,在更高的能量下,传统的闪烁体迅速成为限制因素。它们必须薄而才能提供合理的空间分辨率并保持图像质量。然而,由于低停止功率,厚度不足介绍了对长采集时间的需求。为了解决这些问题,我们合成了一种新的结构闪烁器,将其集成到基于CCD或光电二极管的CT系统中。铕掺杂的LU_2O_3(LU_2O_3:EU)在所有已知的闪烁体中具有最高密度,X射线的极高吸收系数和亮度与底层CCD-和光电二极管阵列的量子效率很好。当耦合到合适的探测器时,该微校展闪烁体显着提高了检测器的总检测量子效率。由Lu_2O_3的第一次,结构化和闪烁薄膜:EU通过电子束物理气相沉积生长。使用实验室X射线源以及同步辐射产生原型传感器和评估。进行了新开发的传感器与商业级闪烁体的比较绩效评估。这种高密度,微结构,闪烁涂层的合成使得能够开发用于CT应用的高灵敏度X射线探测器。

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