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Single-scan energy-selective imaging on cone-beam CT: a preliminary study

机译:锥形束CT的单扫描能量选择性成像:初步研究

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On an onboard cone-beam CT (CBCT) system, the poly-energetic beam generated by current commercial x-ray tubes hardens as it penetrates the object. The beam-hardening effect results in CT image artifacts of up to 100 HU, especially around dense objects (e.g. bones). We propose to insert a half-blocked beam filter between x-ray source and object, such that any ray passing through the object is filtered once from one of the opposite directions in a single full scan. The conventional data processing of dual energy imaging is then applied to obtain material decomposition as well as CT images with no beam-hardening artifacts. In this preliminary study, we demonstrate the method feasibility using computer simulations. The beam filter thickness is optimized to balance the CT number accuracy and the noise level on the reconstructed images via both analytical calculation and measurement of image noise. A calibration phantom is designed to obtain the decomposition function for energy selective imaging by projection measurements without the knowledge of x-ray spectrum and detector response. Using the optimized beam blocker and the calibration phantom, we simulate the data acquisition using scan settings of a commercial CBCT system. Our proposed approach significantly suppresses beam-hardening artifacts and reduces the image error from 65 HU to 9 HU in the selected regions of interest on a head phantom. The method also successfully decomposes bone and soft tissue, with 95% accuracy.
机译:在机载锥形束CT(CBCT)系统上,当前的商用X射线管产生的多能束在穿透物体时会变硬。光束硬化效应会导致高达100 HU的CT图像伪影,尤其是在密集物体(例如骨骼)周围。我们建议在X射线源和对象之间插入一个半遮挡的光束滤镜,以使穿过对象的任何光线在一次完整扫描中从相反方向之一被过滤一次。然后应用双能量成像的常规数据处理来获得材料分解以及没有束硬化伪像的CT图像。在这项初步研究中,我们通过计算机仿真证明了该方法的可行性。通过对图像噪声进行分析计算和测量,可以优化光束滤波器的厚度,以平衡CT数的准确性和重建图像上的噪声水平。校准体模被设计为通过投影测量获得能量选择性成像的分解功能,而无需了解X射线光谱和检测器响应。使用优化的光束阻挡器和校准体模,我们使用商业CBCT系统的扫描设置来模拟数据采集。我们提出的方法可显着抑制束硬化伪影,并将头部模型上感兴趣的选定区域中的图像误差从65 HU降低到9 HU。该方法还可以成功分解骨头和软组织,准确率达95%。

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