首页> 外文会议>ASME summer bioengineering conference;SBC2012 >INNOVATIVE THERAPEUTIC KIT FOR MAGNETICALLY CONTROLLED VISCOSUPPLEMENTATION TREATMENT OF KNEE OSTEOARTHRITIS
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INNOVATIVE THERAPEUTIC KIT FOR MAGNETICALLY CONTROLLED VISCOSUPPLEMENTATION TREATMENT OF KNEE OSTEOARTHRITIS

机译:磁控骨关节炎的磁控增粘治疗的创新治疗套件

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The therapeutic attitude for degenerative knee joint damage (such as osteoarthritis) consists in a complex protocol which starts with physiotherapy sessions, involves the use of specific devices - orthosis for sustaining the affected joint, and includes intra-articular infiltrations for reducing the pain, improving joint mobility and minimizing functional deterioration [1,2]. Magnetically controlled viscosupplementation restores the viscoelastic qualities of the synovial fluid, improving the rheology as a result of controlled degradation of hyaluronate into the joint. This therapy requires a mix approach, combining the advantages offered by intra-articular therapy with the use of a special designed orthosis (oriented to the specific place of the articular lesion) containing permanent magnets. The magnetic field created by the magnets placed on the orthosis, localizes and concentrates the injected fluid with magnetic nanoparticles, enhancing the targeted delivery of the active substances [3].
机译:退行性膝关节损伤(例如骨关节炎)的治疗态度包括一个复杂的方案,该方案从物理治疗开始,涉及使用特定装置-矫形器以维持受影响的关节,并包括关节内浸润以减轻疼痛,改善疼痛关节活动度并使功能恶化减至最小[1,2]。磁控制的粘液补充可恢复滑液的粘弹性质,由于透明质酸盐向关节的受控降解而改善了流变性。这种疗法需要一种混合方法,将关节内疗法提供的优势与使用专门设计的包含永久磁铁的矫形器(针对关节病变的特定位置)相结合。放置在矫形器上的磁铁产生的磁场使注入的流体与磁性纳米颗粒一起定位并集中,从而增强了活性物质的靶向输送[3]。

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