INTERFACIAL FRACTURE STRENGTH MEASUREMENT OF TISSUE-BIOMATERIAL SYSTEMS

摘要

The interfacial mechanics at the bone-implant interface is a critical issue for implant fixation and the filling of bone defects created by tumors and/or their excision. The present study is based on the hypothesis that the differences of the surface roughness at bone/ implant interface due to incorporation of micro and nano nanoparticle additives may have significant influence on the quality of bone/implant union. This research studied poly Methyl MethAcrylate (PMMA) bone cement with and without MgO additives as different implant materials. The aims of this research were to determine the influences of a magnesium oxide (MgO) additive particle size to PMMA bone cement on the bonding strength between bone and bone cement specimens. The scope of work for this study were: (1) to quantify elastic properties (Young's modulus and Poisson's ratio) of bone cement specimens, (2) to determine whether inclusion of MgO particles with PMMA has any influence on the interface strength between bone and PMMA, and (3) to quantify the effect of surface roughness on the interface fracture strength between bone and PMMA. This study found that the mean interface strength for bone-PMMA is significantly less than the mean interface strengths of bone-PMMA with microsize MgO particles and bone-PMMA with nanosize MgO particles.