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Biomechanical Characterization of a New Titanium Foam Applied As Bone Substitute in Orthopaedic Applications

机译:一种新型钛泡沫在骨科应用中的骨替代物的生物力学表征

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Intervertebral body fusion devices are a promising biomedical application for metal foams. A new Titanium foam made by powder metallurgy was developed and biomechanically assessed to determine its applicability to spinal fusion implants. Mechanical behaviour of a lumbar spinal cage made of this new Ti foam was evaluated under different loading conditions and compared to other cages with similar geometry but different materials. An implantation study was carried out to assess the osseointegration ability of the Ti foam. Bone ingrowth and fixation strength of porous Ti were compared to those of dense Ti with plasma-sprayed Ti and Hydroxyapatite porous coating through push-out mechanical tests and histological analysis. Ti foam implants show high mechanical strength and fatigue endurance. Their stiffness is much closer to that of trabecular bone than solid alloys usually applied to orthopaedic implants. Osseointegration study reveals bone ingrowth inside Ti foam and high bonding strength for this material. However, bone fixation strength is lower than that obtained by solid plasma-sprayed coated implants.
机译:椎间融合器是金属泡沫的有前途的生物医学应用。开发了一种通过粉末冶金制成的新型钛泡沫,并对其进行了生物力学评估,以确定其在脊柱融合植入物中的适用性。在不同的载荷条件下评估了这种新型Ti泡沫制成的腰椎脊柱保持架的力学性能,并将其与具有相似几何形状但材料不同的其他保持架进行了比较。进行了植入研究以评估Ti泡沫的骨整合能力。通过推出的力学测试和组织学分析,将多孔Ti的骨长入和固定强度与等离子喷涂Ti和羟基磷灰石多孔涂层的致密Ti的骨长入和固定强度进行了比较。钛泡沫植入物显示出较高的机械强度和耐疲劳性。与通常用于整形外科植入物的固态合金相比,它们的刚度更接近小梁骨。骨整合研究显示,Ti泡沫内部骨骼向内生长,并且这种材料具有很高的粘结强度。但是,骨固定强度低于通过固体等离子喷涂涂层植入物获得的固定强度。

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