CONTROLLED RELEASE AND INTRACELLULAR DELIVERY OF SMALL MOLECULES USING THERMALLY RESPONSIVE PLURONIC F127-CHITOSAN NANOCAPSULES

摘要

Nanoscale participate systems have been studied as the delivery vehicle of various drugs and therapeutic agents for decades with promising outcomes. Recently, nano-particulate systems that are responsive to one or more environmental stimuli (such as temperature, pH, and electromagnetic field) are attracting increasing attention because they allow drug delivery and release to be done in a more controllable fashion [1].