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Design, optimization and testing of a multi-beam micro-CT scanner based on multi-beam field emission x-ray technology

机译:基于多光束场发射x射线技术的多光束微CT扫描仪的设计,优化和测试

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As a widely adopted imaging modality for pre-clinical research, micro-CT is constantly facing the need of providing better temporal as well as spatial resolution for a variety of imaging applications. Faster CT scanning speed is also preferred for higher imaging throughput. We recently proposed a gantry-free multi-beam micro-CT (MBμCT) design which has the potential to overcome some of the intrinsic limitations of current rotating-gantry CT technology. To demonstrate its feasibility, we have constructed a testing system with a multi-beam field emission x-ray (MBFEX) source array with a linear array of 20 individually controllable x-ray emitting pixels. Based on simulations of the electron optics and preliminary experimental measurements the design of the MBFEX source has been further optimized. The newly designed imaging system has been characterized and commissioned following our standard imaging protocol. It has clearly shown improved system stability and enhanced imaging capability. As a result of reduced mechanical rotation during imaging acquisition, we are expecting to achieve higher CT scanning speed without significantly sacrificing imaging quality. This prototype MBμCT system, although still in its early development phase, has been proved to be an ideal testing platform for the proposed gantry-free micro-CT scanner.
机译:作为临床前研究中广泛采用的成像方式,微型CT一直面临着为各种成像应用提供更好的时间和空间分辨率的需求。对于更高的成像吞吐率,也优选使用更快的CT扫描速度。我们最近提出了一种无机架多波束微型CT(MBμCT)设计,该设计有可能克服当前旋转机架CT技术的某些固有局限性。为了证明其可行性,我们构建了一个具有多光束场发射X射线(MBFEX)源阵列的测试系统,该阵列具有20个可单独控制的X射线发射像素的线性阵列。基于电子光学的仿真和初步的实验测量,MBFEX源的设计得到了进一步的优化。新设计的成像系统已按照我们的标准成像协议进行了表征和调试。它清楚地显示出改进的系统稳定性和增强的成像能力。由于减少了成像采集过程中的机械旋转,我们期望在不显着牺牲成像质量的情况下实现更高的CT扫描速度。该原型MBμCT系统虽然仍处于早期开发阶段,但已被证明是所建议的无机架微CT扫描仪的理想测试平台。

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