Organic fluorescence agent designed into nanoparticle can significantly promote its fluorescent efficiency. In this pape; a novel fluorescein isothiocyanate labeling aminated agarose (FITC-AA) is prepared and tested as an effective fluorescent labeling agent. IR analysis and EA proved that FITC was grafted to the aminated agarose (AA) successfully. FITC-AA spontaneously formed nanoparticle with a diameter between 159.2 nm and 1530 nm at below 37°C by gelling effect of agarose. Cell culture experiments confirmed that HL-60 cells and 3T3 fibroblast cells could be fluorescently marked by FITC-AA nanoparticles and their fluorescence sustained longer than by FITC. After deposited for half a year; FITC-AA can reversibly dissolve in hot water and form nanoparticles when cooling to 37°C; and its fluorescent properties remain. These findings demonstrate that FITC-AA is an effective labeling agent for marking cells.;
机译:两种新型68Ga标记的5-硝基咪唑衍生物的合成,体外和体内特性表征,这些潜在的成像缺氧剂
机译:新型99mTc-'4 + 1'标记的5-硝基咪唑衍生物的合成,体外和体内表征
机译:(18)F标记的氟烷基苯丙氨酸类似物作为潜在的PET成像剂的合成,吸收机制表征和生物学评估。
机译:FITC-胺化琼脂糖为高荧光标记剂的合成与表征
机译:TELLURIUM-123(M)标记的脂肪酸和巴比妥酸酯:合成,鉴定和用作心肌和脑的成像剂。
机译:18°F标记氟烷基苯丙氨酸类似物作为潜在宠物成像剂的合成摄取机理表征及生物学评价
机译:18°F标记氟烷基苯丙氨酸类似物作为潜在宠物成像剂的合成,摄取机理表征及生物学评价
机译:基于雄激素受体的前列腺成像剂:用氚和氟-18标记的雄激素进行合成和组织分布研究