Individualized cortical function mapping using high gamma activity

摘要

How to reduce the risk of damaging the epilepsy patient's vital function areas during resection of epileptic focus remains a challenge for neurosurgeon. Clinically used electrical cortical stimulation (ECS) method shows limits on accuracy, efficiency and reliability. In this study, a cortical function mapping method with 3D visualization was implemented by analyzing and projecting the power change of high gamma (HG) oscillation in ECoG on patient's own MRI brain model. The method was tested on epilepsy patients with subdural electrodes for three tasks (hand movement, tongue movement and silent reading). The proposed 3D cortical function mapping on the patient's individual brain structure provides direct and accurate reference for resection surgery planning.