A Novel Skin-Care Product Based on Silk Fibroin Fabricated by Electrospinning

摘要

A novel Vitamin C (VC) loaded silk fibroin (SF) nanofibers was fabricated by electrospinning with blend aqueous solution of the materials. The morphology of electrospun VC loaded SF (VC/SF) nanofibers was observed by scanning electronic microscope (SEM) and the compositions of the composite nanofibers were inspected by X-ray photoelectron spectroscopy (XPS). The nanofibrous membrane was post-treated by methanol vapor, which rendered the nanofibers a good water-insoluble characterization. After soaked into phosphate buffered saline (PBS) for 4 days, the water-insoluble nanofibers have swelled due to the absorbing of water. The electrospun SF nanofiber membrane could be a more effective vehicle to delivery the VC into skin tissue and this novel product of VC/SF composite nanofiber is expected to have a good prospect of application on skin care, wound dressing and skin tissue engineering.