Quantitative acousto-optic imaging in tissue-mimicking phantoms

摘要

We have investigated the application of acousto-optic sensing for quantitative imaging of tissue-mimicking phantoms. An Intralipid phantom, which contains a turbid absorber, confined in a silicone tube, was used. Scattered pulsed laser light was modulated by ultrasonic bursts focused in a predefined volume in the medium. By varying the delay time between ultrasound burst initiation and light pulse firing we could perform a scan in the ultrasound-propagation plane. The use of calibration procedures allowed us to establish a quantitative correlation between local absorbances in the phantom and the measured signal and to obtain information on the ratios of dye concentrations inside the tube.