Phagocytosis of Fullerene Nanowhiskers by PMA-treated THP-1 Cells

摘要

We observed phorbol 12-myristate 13-acetate (PMA)-treated THP-1 cells (macrophage-like cells) exposed to 10 μg/mL of short (< 20 μm) C_(60) fullerene nanowhiskers (C_(60)NWs) with a differential interference contrast and confocal laser microscope to locate the position of C_(60)NWs among cells three-dimensionally. The number of macrophage-like cells internalising C_(60)NWs increased with time and more than 70% of the cells internalised the C_(60)NWs after 48 h of the C_(60)NWs' exposure.