A new method for measuring Auto-Fluorescence changes in neovascular-AMD after intravitreal injection of Bavecizumab

摘要

Age-related macular degeneration (AMD) is the second disease diabetes which causes blindness in aged people. The only remedy for AMD is intravenous injection of Bavecizumab. To prove the efficiency of remedy, the degenerated cells in macula should be measured. In this paper, the new software is introduced to measure auto-fluorescence in macula part of retina in order to determine the number of degenerated cells. This system is consists of three main parts: low level pre-processing, image analysis and images understanding. Experiments have been done on a database of 34 retina images of before and after AMD patients remedy. The average number of decreased degenerated cells after remedy was 15134. In clinical reviews, the founded relation to disinflation of macula has been proved, while there were no proved relations to the vision decreasing or increasing of patients.